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br Conflict of interest br
2021-04-20
Conflict of interest Acknowledgements This work was supported by the Biotechnology Research Center, China Three Gorges University, Yichang, China (No. 2016KBC05), the National Natural Science Foundation of China (No. 31370600 and 31300508), the Zhejiang Science and Technology Major Program on
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br Conclusions Taken together the roles of CDK and
2021-04-20
Conclusions Taken together, the roles of CDK8 and miR-152-3p in the process of HCC likely performed opposite effect completely. Both CDK8 and miR-152-3p could serve as the independent prognostic factors for predicting the OS and DFS in HCC patients. We identified that miR-152-3p as a post-transcr
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The data presented above clearly
2021-04-20
The data presented above clearly indicate an important role of eIF4E for the nucleocytoplasmic transport of the human iNOS mRNA. To analyze the sequence elements of the iNOS mRNA that are important for this eIF4E-mediated transport we performed transient transfection experiments using constructs con
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Growing evidence has shown that ANS
2021-04-19
Growing evidence has shown that ANS dysregulation, indexed by heart rate variability (HRV), plays a critical role in the pathogenesis of anxiety (Minassian et al., 2014, 2015). Indeed, we have previously reported that patients with GAD are associated with reduced resting parasympathetical (vagal) co
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Introduction Human cytomegalovirus CMV is a herpesvirus whic
2021-04-19
Introduction Human cytomegalovirus (CMV) is a herpesvirus which has a ubiquitous and worldwide distribution, and is the most frequent cause of congenital infection (Kenneson and Cannon, 2007). The prevalence is around 0.5–1% of all live births and is the leading cause of sensorineural hearing loss
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To our knowledge immunohistochemical analysis for proGRP was
2021-04-19
To our knowledge, immunohistochemical analysis for proGRP was done in 5 cases [9], [10], [17], [18]. Takagi-Takahashi et al. reported that the tumor Arylquin 1 sale were positive for proGRP in one case [9]. Yamaguchi et al. also showed that tumor cells in two patients of ES/PNET with elevated serum
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br Materials and methods F philippinensis plants were collec
2021-04-19
Materials and methods F. philippinensis plants were collected in August 2014 at a farm in Ninning, Guangxi province, China and identified by Dr. Yimmin Zhao. Voucher specimens (No. 530) were deposited in the Herbarium of Gaunxi Botanical Garden, China. Human recombinant neutrophil elastase (EC 3.
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We found that the postnatal
2021-04-19
We found that the postnatal absence of norepinephrine yields differing effects depending on noradrenergic receptor type and Caspase-9 Colorimetric Assay Kit synthesis region. The density of α1-AR, indicated by [3H]prazosin binding was similar between Dbh+/− and Dbh−/− mice except for a significant
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br Acknowledgement br Introduction Human dihydroorotate dehy
2021-04-19
Acknowledgement Introduction Human dihydroorotate dehydrogenase (hDHODH), a flavin-dependent mitochondrial enzyme involved in de novo Gastrodin australia biosynthesis, is a validated therapeutic target for the treatment of autoimmune diseases such as rheumatoid arthritis and cancer [1], [2], [
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It was demonstrated that the addition of
2021-04-19
It was demonstrated that the addition of 10-fold excess of α-synuclein without modifications (with respect to the molar concentration of tetrameric GAPDH) leads to partial inactivation of GAPDH after 1-h incubation by 20% (Fig. 4, curve 2) in Deferasirox mg to insignificant decrease of the specific
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Apamin Besides being an energy storing tissue adipose tissue
2021-04-17
Besides being an energy storing tissue, adipose tissue acts as an active endocrine organ that secretes a number of biologically active adipokines involved in multiple physiological processes such as inflammation and lipid and glucose metabolism, with direct and indirect effects on reproduction [15,1
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Unlike many forms of SNHL cCMV may
2021-04-17
Unlike many forms of SNHL, cCMV may be treatable. The antiviral drug valganciclovir (VGCV) has been proposed to improve hearing, speech, and language outcomes associated with this infection [6]. A recent publication from the CASG (Collaborative Antiviral Study Group) reported that a six-month course
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Even minor alterations in the surfactants structure
2021-04-17
Even minor alterations in the surfactants structure could have consequences on their physico-chemical characteristics; mono-RLs have less solubility, stronger surfaces sorb, and stronger cationic metals binding than homologue di-RLs (Zhang et al., 1997). The HPLC separation of RLs structure is base
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br Experimental Procedures br Acknowledgments br Bisphenol
2021-04-17
Experimental Procedures Acknowledgments Bisphenol A (BPA) has been recognized as one of the most potent endocrine disruptors, functioning even at very low doses. Although it is anticipated that Forskolin receptor (ER) would mediate these effects of low-dose BPA, studies revealed that BPA bo
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It was demonstrated that ET signaling is
2021-04-17
It was demonstrated that ET-1 signaling is the primary axon guidance mechanism that accounts for sympathetic innervation of the sinoatrial node and myocardium in the developing mouse heart [11]. In this article, we will review the findings relating to the basic profiles; i.e. molecular features of
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