• The use of AACSB accreditation as an indicator

  2020-11-09

  

  The use of AACSB accreditation as an indicator of expected performance on the CPA exam has been examined by prior studies (e.g. Barilla et al., 2008, Boone et al., 2006, Grant et al., 2002, Howell and Heshizer, 2006, Lindsay and Campbell, 2003, Marts et al., 1998). While these studies are based on d

• The main variable of the study was whether there was

  2020-11-09

  

  The main variable of the study was whether there was an association between the COMT Val158Met polymorphism and motor behavior. Additionally, it was investigated whether the effects of the COMT genotypes on the role played by tonic/phasic DA are associated with the stability/flexibility nature of th

• Moreover as shown in Fig

  2020-11-09

  

  Moreover, as shown in Fig. 5f, while the knockdown of SMURF2 in wild-type RWJ 56110 synthesis has no significant effect on HSP27, in CK2α/α′(−/−) cells it leads to an increase of HSP27 level. These results suggest that SMURF2 affects HSP27 protein stability only when overexpressed, at least in our

• An interesting observation pertinent to the immunology of pr

  2020-11-09

  

  An interesting observation pertinent to the immunology of pregnancy comes from a study by Kruse et al., they found that recurrent miscarriage patients with higher serum progesterone levels had lower Th1/Th2 cytokine ratios suggesting that progesterone levels modulate cytokine production patterns. Pr

• When women reach the menopause they experience a number of

  2020-11-09

  

  When women reach the menopause they experience a number of physical complaints such as hot flushes, vaginal dryness and mood changes [1]. Bone loss also becomes manifest at this time [1], [2], but women will often not suffer from back pain before a vertebral fracture occurs. Women who have had one f

• br Discussion We are reporting

  2020-11-09

  

  Discussion We are reporting a cryptic insertion of chromosome 22 material (EWS) to the long arm of chromosome 11 (11q24, FLI-1) recognizable by FISH in KB SRC 4 exhibiting trisomy 8 as the sole cytogenetic anomaly. In ES and PNET tumors, trisomy 8 is the most common secondary abnormality [6]. Ad

• The presence of a vicious cycle established

  2020-11-09

  

  The presence of a “vicious cycle” established between tumor proliferation and paratumor osteolysis plays a crucial role in the development of primary bone tumors [53]. Cancer cells produce soluble factors that activate directly or indirectly via osteoblasts, osteoclast differentiation and maturation

• Recent studies have reported that

  2020-11-09

  

  Recent studies have reported that miR-454 plays an important role in various cellular processes and diseases, such as inflammation, infection, osteogenic differentiation, and cancers [25,27,29,30]. Multiple evidence has documented that miR-454 promotes the proliferation, migration and invasion, and

• In looking at exist http www

  2020-11-09

  

  In looking at existing FGE substrates from other organisms, there are no reported effects on conversion efficiency of the general XCXPXRX pattern with respect to placement within or at the N′ or C′ terminus of polypeptides, and it has been suggested that the aldehyde formation is independent of the

• mi2 mg Nrf and HO are key factors in the regulation of

  2020-11-09

  

  Nrf2 and HO-1 are key factors in the regulation of oxidative stress in the body. Research has shown that KLF2 can activate Nrf2 and HO-1 [14]. To investigate the mechanisms by which KLF2 regulates eNOS uncoupling and oxidative stress, Nrf2 was inhibited or HO-1 was knocked down in KLF2 overexpressin

• Our studies approached this problem using integrative omics

  2020-11-09

  

  Our studies approached this problem using integrative -omics analysis of human NK-ieILC1s from distinct microenvironments and functional subsets, including helper and adaptive phenotypes. At both the transcriptional and epigenetic levels, we find that the adaptive subset, CD57+ cytotoxic NK cells, s

• Given the link between E s autoimmunity and antitumor immuni

  2020-11-09

  

  Given the link between E3s, autoimmunity, and antitumor immunity, it Cy5 azide synthesis is reasonable to assume that, similar to other ICBs, IRAEs may limit the clinical use of E3-targeting therapies – further stressing the need to better understand the underlying mechanisms of these unwanted effe

• The ubiquitin proteasome system Ub P is the

  2020-11-09

  

  The ubiquitin–proteasome system (Ub–P) is the main cellular machinery for protein turnover in eukaryotic cells (Glickman and Ciechanover, 2002). Degradation by Ub–P involves two steps. Target proteins are selectively, specifically, and covalently attached to ubiquitin (Ub) chains, followed by Ub-tag

• br Discussion Several DPP inhibitors are currently

  2020-11-06

  

  Discussion Several DPP-4 inhibitors are currently available for use in the treatment of type 2 diabetes mellitus. Due to the different chemical structures there are marked differences both in the binding kinetics on the target enzyme [10] and also different pathways of elimination [13] exist. In

• QSAR based on the D structures of ligands

  2020-11-06

  

  QSAR based on the 3D structures of ligands plays an important role in the ligand-based drug discovery and design [12]. Comparative molecular field analysis, CoMFA [11], and comparative molecular similarity index analysis, CoMSIA [12] are among the most popular QSAR models. They focus on changes in 3

15138 records 766/1010 page Previous Next First page 上5页 766767768769770 下5页 Last page