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Many authors have described the existence
2020-01-11

Many authors have described the existence of correlation between viability and moisture content and therefore, water availability. Sabuquillo et al. (2010) demonstrated that only Penicillium oxalicum conidial formulations whose initial moisture contents ranged between 5 and 14% retained their viabil
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Acknowledgments br Introduction Diabetes mellitus DM
2020-01-11

Acknowledgments Introduction Diabetes mellitus (DM) is a multifactorial disease [1] associated with serious comorbidities. This condition has recently reached epidemic proportions, as its occurrence has exponentially increased in the general population. Over 400 million people worldwide were est
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br Acknowledgments br Introduction Heterocyclic
2020-01-11

Acknowledgments Introduction Heterocyclic chemistry has become one of the most important fields of research in pharmaceutical industry due to their many fold applications. Amongst all, heterocyclic it is impossible containing nitrogen and oxygen have shown most potent biological activities. It
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Introduction Progesterone also known as P
2020-01-11

Introduction Progesterone, also known as P4, is a steroid hormone acting as a key component in the complex regulation of female reproductive function. P4 plays major physiological roles in the uterus and ovary by releasing mature oocytes helping in implantation and maintenance of pregnancy, as well
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br Objectives br Study design Thirty KTx http
2020-01-11

Objectives Study design Thirty KTx recipients were enrolled in this pilot study from December 2015 to May 2016. Patient demographics are presented in Table 1. The inclusion criteria were: age ≥ 18 years and CMV-IgG serostatus (D+/R−, D+/R+, D−/R+) pre-Tx. All patients were enrolled during the
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In the Cu bioassay notwithstanding the absence of
2020-01-11

In the Cu bioassay, notwithstanding the absence of significant Cu bioaccumulation in bulk tissues over the 96-h exposure period (less than 2-fold difference in tissue Cu between controls and the second-highest treatment), T-ChE activity increased with Cu concentration in gill and, to a lesser extent
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The mechanism underlying the increased
2020-01-11

The mechanism underlying the increased PON1 levels found in greenhouse workers may be accounted for by an increased protein pim inhibitor following pesticide interaction with different nuclear receptors as also occurs with other chemicals, such as polyphenols and statins [28]. A number of nuclear r
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br Regulation of cadherin switching The downregulation
2020-01-11

Regulation of cadherin switching The downregulation of E-cadherin during cadherin switching is induced by multiple mechanisms, including methylation of the E-cadherin promoter and signaling pathways that activate E-cadherin-suppressing transcription factors [[61], [62], [63]]. During the progress
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Generally glycines and other small
2020-01-11

Generally, glycines (and other small residues such as alanine) present in a helical GxxxG-motif that are facing the same side of the helix form a uniform surface that enables direct contact with a second helix. Crystal structures of multipass membrane proteins have demonstrated that GxxxG-motifs are
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br Conclusions br Acknowledgement Grant support Ministry of
2020-01-10

Conclusions Acknowledgement Grant support: Ministry of Health (n. of grant: RBAP10447J_004 to N. Baldini), Italian Association for Cancer Research (n. of grant: 11426 to N. Baldini). Introduction Ewing sarcomas (ES) and primitive neuroectodermal tumors (PNET) are related childhood tumors.
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Mulan protein level is regulated with conditions
2020-01-10

Mulan protein level is regulated with conditions that stimulate mitophagy such as treatment of Caspase-7, human recombinant protein with CCCP [12]. We found that exogenously expressed GFP-GABARAP and RFP-Mulan could co-precipitate and co-localize in mammalian cells and the degree of co-localization
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Eggs have been recognized as an important contributor of
2020-01-10

Eggs have been recognized as an important contributor of functional ingredients for humans [3]. Egg yolk is composed of various biologically active proteins. The water-soluble proteins of egg yolk have been examined for their functional effects on longitudinal bone growth during the growth period in
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br Synthesis and mechanism of fluorescent DNA
2020-01-10

Synthesis and mechanism of fluorescent DNA-CuNMs Application of fluorescent DNA-CuNMs Summary and conclusions In summary, we introduce recent research progress in the synthesis and various applications of DNA-CuNMs. DNA-CuNMs with novel catalytic, electrical and optical properties can be ob
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DGK type I http www apexbt com
2020-01-10

DGKη1 (type II DGK) has a separated catalytic domain [10], [13], whereas the domains of DGKα, ε and ζ are not split [1], [2], [3], [4], [5]. Therefore, the structural difference may cause the distinct affinity for DG among these isozymes. Because other type II DGKs (η2, δ1, δ2 and κ) also have the s
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p is a tumor suppressor gene that inhibits cyclin dependent
2020-01-10

p16 is a tumor-suppressor gene that inhibits cyclin-dependent kinase 4 and 6 activities and arrests the ache inhibitors in the G1 phase. Aberrant methylation and mutation of p16/MTS1 in OSCC of patients was found in our previous study. Moreover, the frequency of hypermethylation of p16 from the pre
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